Local Scientific Community Goes Global

 
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The World Congress of Nephrology (WCN) is the leading biennial educational event in international nephrology and was held in Hong Kong from May 31–June 4 2013. Australia was well represented at the WCN this year with over 70 scientific abstracts being presented.

These contributions spanned multiple research categories, including:

  • Clinical studies in renal transplantation (13)
  • Haemodialysis (12)
  • Epidemiology, outcomes and health service research in CKD (5)
  • Peritoneal dialysis (5)
  • Renal pathology, experimental pathology, including immune and inflammatory mechanisms (5)
  • Cell signaling, cell growth control, hormones and cytokines (3)
  • Biomarkers for acute kidney injury (3)
  • Clinical studies including toxic nephropathy (3)
  • Complications of dialysis (2)
  • Clinical nephrology (2)
  • Acute renal failure - experimental models (2)
  • Transplantation: basic science and immune tolerance (2)
  • Nutrition (CKD and ESKD) (2)
  • Vascular access in dialysis (2)

One of the posters was presented in the Peritoneal Dialysis category by Cho and colleagues. It described a systematic review evaluating the impact of peritoneal dialysis (PD) solutions, characterised by low glucose degradation products (GDP) and neutral pH, on clinical outcomes.1
Twenty eligible trials, including 1383 patients, were analysed and results showed that the use of neutral pH, low GDP PD solutions was associated with:1

  • Larger urine volumes in trials of up to three years’ duration (7 trials; 522 patients; mean difference 126.35 mL/day, 95% confidence interval [CI] 26.92–225.78)
  • Improved preservation of residual renal function (RRF) in trials of >12 months’ duration (6 trials; 360 patients; standardised mean difference 0.31, 95% CI 0.10–0.52)
  • No significant effect on peritonitis or technique failure.

The authors concluded that, based on the best available evidence, the use of neutral pH, low GDP PD solution results in clinically relevant benefits without added harm.1

To review additional abstracts presented at WCN 2013, please click here.

References:

  1. Cho Y, Johnson DW, Badve SV et al. Impact of neutral pH, low glucose degradation product peritoneal dialysis solution on clinical outcomes in peritoneal dialysis: a systematic review of randomised controlled trials. Presented at the: World Congress of Nephrology (WCN). Hong Kong, May 31–June 4 2013: Abstract SA422.